Wednesday, August 20, 2008

Fingolimod and Me

Fingolimod and Me
Last week I thought we were only waiting for the main trial HQ in Berlin to approve my MRI. Now I have to get chunks of skin cut off like some sick hazing ritual to prove I am worthy of continuing with Fingolimod.

Truth be told, I'd probably let them shave me bald and tattoo "STUPID" across my forehead if it meant a new bottle of pills. I've become such a Fingolimod junky. Sheesh.
http://fty720.blogspot.com/



Suppressing Disease-Causing Genes Is Now Within Reach
Mount Sinai researchers have developed a new gene silencing technology that could be used to target genes that can lead to the development of certain diseases. This technology could pave the way for preventing diseases where gene dysfunction plays a role.



Expert Neurology Panel Weighs Impact of New Reports of PML in ...
Earthtimes (press release) - London,UK
New interferons, integrin inhibitors, B-cell inhibitors, S1Ps, fumarates, neuroprotection/neuroregeneration. -- The potential for vaccine or MAb approaches ...
See all stories on this topic


Medical microbiology

Immune Response to Human Embryonic Stem Cells in Mice Suggests ...
MarketWatch - USA
Davis, who is also an investigator for the Howard Hughes Medical Institute, is a co-author of the paper, which will be published Aug. ...
See all stories on this topic

Stanford scientists suggest stem-cell monkey-wrench
Bizjournals.com - Charlotte,NC,USA
Wu and Davis — a professor of microbiology and immunology at Stanford — used new molecular imaging methods to watch cells live or die inside the mice during ...
See all stories on this topic

Peplin's $24M Private Placement to Fund Phase III Keratosis Trial
TMCnet - USA
Those proceeds will support a new drug application filing in the first quarter of 2009 as well as premarketing activities for Fampridine-SR, a drug intended ...
See all stories on this topic
Too Much Punishment for Amylin

Motley Fool - USA
... Elan (NYSE: ELN) and Biogen Idec (Nasdaq: BIIB) had to deal with new cases of a brain disorder in patients using their multiple sclerosis drug Tysabri. ...
See all stories on this topic

Managing chronic health conditions explored
Eureka Times-Standard Wed, 20 Aug 2008 1:40 AM PDT
The key to living with chronic health conditions -- whether it's diabetes, heart disease or multiple sclerosis or arthritis -- is developing one's management skills.

Biogen Idec reports 2nd-quarter results with Wall Street focused ...
CanadianBusiness.com - Toronto,Ontario,Canada
... the company and its partner Genentech Inc. said their drug Rituxan failed a mid- to late-stage study for primary-progressive multiple sclerosis, ...
See all stories on this topic


Complementary and Alternative Therapies

Dr. Yeung

Director MS Clinical Trials Research Unit Foothills MS Clinic, Calgary
View BIO


Q :


I read a article written by a popular radio personality doctor, who wrote that because his blood levels of vitamin D are low in winter - he has chosen to use UVB tanning lamps as opposed to supplements, because of a study from Australia which suggests that vitamin D supplement use may retard the body's ability to make vitamin D on its own. What are your thoughts on this?


A :


I am unable to find the Australian study that he mentions in this article; through a search of the medical literature, there are no studies that mention this association. However, there are numerous studies that show exposure to UVB (the ultraviolet radiation (UVR) required to convert 7-dehydrocholesterol to vitamin D) and any type of UVR (artificial or solar) can have significant side effects. UVR is a known carcinogen and excessive exposure to solar UVR increases risk of cancer of the lip, basal cell and squamous cell carcinoma of the skin, and cutaneous malignant melanoma. Solar UVR also increases risk of eye diseases including cataracts, some conjunctival tumours, and perhaps ocular melanoma. Cosmetically, it can increase the appearance of wrinkles and hasten aging. Similar effects likely occur with exposure to UVR from tanning beds. Taking an oral supplement of vitamin D would seem to be a safer alternative to UVR exposure and all its attendant potential side effects.
8/20/2008 3:56:02 PM
8/20/2008 3:56:02 PM
More answers from Dr. Michael Yeung
More answers in the category: Complementary and Alternative Therapies

DISCLAIMER: Please be aware that this information does not necessarily represent the opinion of the MS Society of Canada, and is not intended as medical advice. For specific advice and opinion, always consult a physician.
© 2008 Multiple Sclerosis Society of Canada | www.mssociety.ca

http://www.msanswers.ca/QuestionView.aspx?L=2&QID=2110


http://www.msanswers.ca/QuestionView.aspx?L=2&QID=2110



Create a Healthy Brain Plan

http://alzheimers.about.com/od/prevention/ht/healthybrain.htm?nl=1
Blood Vessel Gene Influences Brain Size, Yale Researchers Find
The size of a key area of the brain involved in memory and mood disorders is influenced by variation in a growth factor gene that influences blood vessel growth and has been widely studied in heart disease and cancer, Yale University researchers have found.
Perspectives in Central Nervous System Malignancies
These 4 podcasts provide additional insights into the PCNSM4: Perspectives in Central Nervous System Malignancies conference, which discussed trends and treatment strategies associated with the management of CNS malignancies.
Source:
Johns Hopkins Advanced Studies in Medicine (JHASiM) [more]
Arsenic in Drinking Water Linked to Type 2 Diabetes
BALTIMORE -- Millions of Americans may be at an increased risk for type 2 diabetes because of arsenic in their drinking water, researchers here said. full story

http://www.medpagetoday.com/Cardiology/Diabetes/tb/10600

Exercise: A drug-free approach to lowering high blood pressure
Exercise is a great way to control your blood pressure. Even small changes in your daily routine can make a big difference.

Doctors checking patients more for vitamin D levels
Seattle Post Intelligencer - USA
By LAURAN NEERGAARD AP WASHINGTON -- Don't be surprised if your doctor orders a vitamin D test during your next physical. Blood tests to check levels of the ...
See all stories on this topic

Researchers produce blood in lab from embryonic stem cells

By Karen Kaplan

The discovery marks a technical advance but has a long way to go before it can be considered an alternative to donor blood. >>

Stem cells used to grow blood in lab
Minneapolis Star Tribune - Minneapolis,MN,USA
Scientists said Tuesday they have devised a way to grow large quantities of blood in the lab using human embryonic stem cells, potentially making blood drives a relic of the past.
See all stories on this topic

Sleep Leads To Better Blood Pressure In Teens
KDKA - Pittsburgh,PA,USA
In adults, less than six hours sleep is associated with high blood pressure. Now, there's the first study to make a connection between blood pressure and ...
See all stories on this topic

Risk of high blood pressure higher among sleepier teens: study
CBC.ca - Toronto,Ontario,Canada
Teenagers who don't get enough shut-eye may not only be drowsy in class, but they could also be increasing their risk for high blood pressure and heart ...
See all stories on this topic


Stem Cell Research News

McCain, Obama Discuss Abortion, Embryonic Stem Cell Research During Forum At Saddleback Church
Presidential candidates Sens. John McCain (R-Ariz.) and Barack Obama (D-Ill.) on Saturday at a forum moderated by the influential evangelical minister Rev. Rick Warren at 19 Aug 2008


Limbs Saved By Menstrual Blood Stem Cells
Cells obtained from menstrual blood, termed 'endometrial regenerative cells' (ERCs) are capable of restoring blood flow in an animal model of advanced peripheral artery disease. A study published in BioMed Central's open access Journal of Translational Medicine demonstrates that when circulation-blocked mice were treated with ERC injections, circulation and functionality were restored.

Stem Cell Indicator For Bowel Cancer Should Lead To Better Survival Rates
Stem cell scientists have developed a more accurate way of identifying aggressive forms of bowel cancer, which should eventually lead to better treatment and survival rates. Bowel cancer is the third most common cancer in the UK.

Plerixafor Treatment Improves Mobilization Of Cells In Donors During Bone Marrow Stem Cell Collection Procedures
In a study of 25 bone marrow donors, treatment with plerixafor, an antagonist able to disrupt a critical pathway associated with stem cell mobilization, was shown to mobilize cells faster than treatment with granular colony-stimulating factor (G-CSF), the current standard method used to collect bone marrow stem cells from healthy donors.

NIH creates new stem cell research center

August 19, 2008

By John Carroll

Tags bone marrow National Institutes of Health Stem Cells Rocky Tuan

http://www.fiercebioresearcher.com/story/nih-creates-new-stem-cell-research-center/2008-08-19?utm_medium=nl&utm_source=internal&cmp-id=EMC-NL-FBR&dest=FBR

The National Institutes of Health told staffers last week that it is setting up a bone marrow-stem cell transplant center within the National Institute for Arthritis and Musculoskeletal and Skin Diseases, according to an article in Wired. The NIH sees the use of adult stem cells to regenerate muscle and bone as a looming opportunity. And in part the field is being driven by the experience of veterinarians, who now regularly use stem cells to treat animals. The use of stem cells to spur muscle growth in horses, for example, has now become almost routine. A precursor procedure that uses platelet rich plasma for injuries is already in use. But it won't be easy to adapt the same methods for horses for human use.

"After a few weeks (of lab growth), it will turn into something that resembles a tendon, but it has to be the mechanical equivalent and we don't know that we're there," said NIH researcher, Rocky Tuan, about one of his stem cell projects. "Stem cells are very promising, but what they do for horses may not work so well for humans because humans are the hardest animal to rebuild."
--read the article from Wired

Related Articles:
Live from BIO: Mass. announces $1B stem cell plan
Stem cell breakthrough propels research on ALS
GSK, Harvard ink stem cell research pact
Pfizer bankrolls a stem cell start-up
California's stem cell boom spurs research bonanza


More Topics


Can the mere possession of a plant land you in jail?


It sure can.
In what must be one of the most bizarre episodes in
all human history, one of the most useful plants known
to man was criminalized by the US government in the
1930s or the benefit of a chemical company, a newspaper
mogul and a banker.
Details here:
http://www.brasschecktv.com/page/409.html
Brasscheck TV
2380 California St.
San Francisco, CA 94115
- Brasscheck

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