Thursday, May 29, 2008

From fish to man: understanding endogenous remyelination in central nervous system demyelinating diseases.

From fish to man: understanding endogenous remyelination in central nervous system demyelinating diseases.

This paper gives an overview of the remyelinating process comparing different species, including humans. They focus on the fact that fish are more efficient at repairing some parts of their central nervous system than people and what we can learn from this.

authors: Dubois-Dalcq M, Williams A, Stadelmann C, Stankoff B, Zalc B, Lubetzki C.

source: Brain. 2008 May 12 [Epub ahead of print]

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UK MS Society article on a decade in the ‘life’ of MS available now

Alan Thompson, Director of the Institute of Neurology in London and Chairman of MSIF’s International Medical and Scientific Board (IMSB), has written an article for the UK MS Society, looking at changes in MS, including understanding of the disease, treatment strategies and advances in MS research over the past 10 years.

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Plan to promote pan-European standards in MS care

In Lubljana on May 7, neurologists, policy makers, and patients' groups came together for a roundtable discussion organised by the European Multiple Sclerosis Platform (EMSP) concerning pan-European inequalities in access to treatments for people with MS. The results of the pan-European MS Barometer study were presented and discussed among high level representatives from the EU institutions, Slovenian government and the medical profession.

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FTY720

Approval for Novartis' generic Betaferon in EU
Therapeutics Daily (subscription) (press release) - Newtown,PA,USA
Swiss drug major Novartis has received approval from the European Commission for Extavia (interferon beta-1b), its generic version of Bayer Schering's ...
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Novartis Looks For Magic Pill
Forbes - NY,USA
The Swiss drugmaker Novartis has been given the green light by the European Commission to sell Extavia, a multiple sclerosis drug. And although the firm has ...
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Novartis gets approval to sell interferon beta-1b in Europe
Pharma Times (subscription) - London,UK
... first step in getting a foothold in the MS market


Facing the Cognitive Challenges of Multiple Sclerosis
Jeffrey Gingold's book, Facing the Cognitive Challenges of Multiple Sclerosis, is an emotional and well-written account of life with one of the most common symptoms of MS - cognitive dysfunction. In telling his story, Gingold gives honest and practical advice about dealing with the frustrations of this "invisible" symptom of MS.

Read the full review here.

MS and Your Feelings
MS and Your Feelings: Handling the Ups and Downs of Multiple Sclerosis by Allison Shadday is the first book to deal exclusively with the emotional impact of MS. If I was to recommend one book about MS, this would be it.

Read the full review here.


MS in focus: Spasticity survey

Our next issue of MS in focus will be on MS and spasticity and we have created a survey for people with MS who experience spasticity.
Results and experiences will be collated and written up for MS in Focus, due out Summer 2008.

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Long term clinical relevance of criteria for designating Multiple Sclerosis as benign after ten years of disease.

In this study the authors followed a large group of people with MS for more than 20 years to assess the evolution of the disease particularly focusing on those with benign MS. 26 years after onset 11% of people had minimal disability suggestive of benign MS and this was associated with female sex, younger age of onset and absence of motor symptoms at presentation.

authors: Costelloe L, Thompson A, Walsh C, Tubridy N, Hutchinson M.

source: J Neurol Neurosurg Psychiatry. 2008 May 13 [Epub ahead of print]

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Cognitive and psychosocial features of childhood and juvenile MS.

The authors assessed the cognitive and psychosocial abilities of children and adolescents with MS. They found that more than half of these people had difficulties in school and everyday activities. The authors concluded therefore that this is an area of critical importance to focus on to help them to manage better.

authors: Amato MP, Goretti B, Ghezzi A, Lori S, Zipoli V, Portaccio E, Moiola L, Falautano M, De Caro MF, Lopez M, Patti F, Vecchio R, Pozzilli C, Bianchi V, Roscio M, Comi G, Trojano M; Multiple Sclerosis Study Group of the Italian Neurological Society. Amato MP, Goretti B, Zipoli V, Portaccio E, Centorrino S, Contri V, Lori S, Falcini M, Comi G, Moiola L, Falautano M, Trojano M, De Caro MF, Lopez M, Patti F, Vecchio R, Gallo P, Grossi P, Bertolotto A, Giampaolo S, Pozzilli C, Bianchi V, Manca I, Masia C, Bergamaschi R, Veggiotti P, Ghezzi A, Roscio M.

source: Neurology. 2008 May 13;70(20):1891-7.

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EXTAVIA Approved In European Union For Treatment Of Multiple Sclerosis, First In Planned Portfolio Of Therapies From Novartis
The European Commission has approved Extavia® (interferon beta-1b) for the treatment of early and relapsing forms of multiple sclerosis (MS) - the first in a new portfolio of medicines from Novartis that is planned to include both established treatments and innovative therapies for patients with MS.


vitamin D

Vitamin D levels should be multiplied by ten for children: study
NutraIngredients.com - Montpellier,France
By Stephen Daniells 28-May-2008 - Raising current vitamin D levels from 200 International Units (IU) to 2000 IU could boost bone health amongst children and ...
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Plainfield doctor touts benefits from Vitamin D
Barre Montpelier Times Argus - Barre,VT,USA
By Mel Huff Times Argus Staff MONTPELIER – A lack of vitamin D, which is produced by skin when exposed to the sun's rays, correlates with a wide variety of ...
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Current Vitamin D Recommendations Fraction Of Safe, Perhaps ...
Science Daily (press release) - USA
ScienceDaily (May 27, 2008) — The current recommended daily allowance (RDA) of vitamin D for children is 200 International Units (IUs), but new research ...
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Study looks at link between vitamin D and prostate cancer risk
The Canadian Press - TORONTO
TORONTO — A new US study contradicts the notion that high blood levels of vitamin D might help protect men from developing prostate cancer - a finding that ...
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High Doses of Vitamin D Found Safe for Adolescents
MedPage Today - Little Falls,NJ,USA
By Todd Neale, Staff Writer, MedPage Today BEIRUT, Lebanon, May 27 -- High weekly doses of vitamin D 3 for a year raise serum 25-hydroxyvitamin D levels ...
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Relationship between Low Ultraviolet B Irradiance [vitamin D] and ...
ProHealth's ImmuneSupport.com - Santa Barbara,CA,USA
Epidemiological data show an inverse relationship between vitamin D levels and breast cancer incidence. This study investigates the relationship of modeled ...
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Study: Teens should increase vitamin D
United Press International - USA
BEIRUT, Lebanon, May 27 (UPI) -- Researchers in Lebanon say teens may take 10 times the US recommended daily allowance of vitamin D of 200 International ...
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Vitamin D doesn't cut prostate cancer risk
Reuters UK - UK
By Will Dunham WASHINGTON (Reuters) - Vitamin D -- the so-called sunshine vitamin -- does not appear to cut a man's risk of getting prostate cancer, ...
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Vitamin D Status Not Associated With Lower Prostate Risk
U.S. News & World Report - Washington,DC,USA
TUESDAY, May 27 (HealthDay News) -- Men with a high blood concentration of vitamin D don't have a reduced risk of prostate cancer, National Cancer Institute ...
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More vitamin D, more benefits
Medill Reports - Washington,DC,USA
by Farah Khan WASHINGTON – Many pediatricians have been reluctant to prescribe supplementary vitamin D, worried it would be too toxic for children. ...
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Google Blogs Alert for: vitamin D

Use of vitamin D in clinical practice by by John J. Cannell, Bruce ...
By Ndut(Ndut)
The recent discovery--from a meta-analysis of 18 randomized controlled trials--that supplemental cholecalciferol (vitamin D) significantly reduces all-cause mortality emphasizes the medical, ethical, and legal implications of promptly ...
Health for All, for Life, for... - http://healthlife-ndut.blogspot.com/

Current vitamin D recommendations may be too low
New research shows that children may benefit from ten times the recommended daily allowance of vitamin D.
Contemporary Pediatrics Magazine - http://contemporarypediatrics.modernmedicine.com/contpeds

Vitamin D doesn’t cut prostate cancer risk
By admin
if vitamin D might protect against prostate cancer, the second most frequently diagnosed cancer in men worldwide. They tracked vitamin D concentrations in the blood of 749 men diagnosed with prostate cancer and 781 men who did not have ...
Health Experiment - http://www.healthexperiment.com

Relationship between Low Ultraviolet B Irradiance [vitamin D] and ...
By feeds@prohealth.com (Sarif B Mohr, Frank...
The fourth paper from this UC San Diego team adds an association between higher vitamin D3 in the body and lower breast cancer risk to similar findings for vitamin D and kidney cancer, ovarian cancer, and endometrial cancer risk. ...
ProHealth Chronic Fatigue Syndrome... - http://www.immunesupport.com

Are You Getting Enough Vitamin D?
For years companies have bombarded our senses with sensational promises to keep us young, help us lose weight, and help us fight disease....what you see on the shelf at Walgreen’s is high-priced, over-branded SnakeOil. Vitamin D ...
Digg / Health / upcoming - http://digg.com/health


multiple sclerosis stem cells

Getting Facts on Stem Cells Research
RedOrbit - Dallas,TX,USA
Visitors were also given the chance to meet charities dealing with diseases such as Parkinson's disease and multiple sclerosis. ...
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Israeli Scientists Recipients of 2008 International Adult Stem ...
PR Newswire (press release) - New York,NY,USA
... help multiple sclerosis and amyotropic lateral sclerosis patients by injecting their spinal fluid with large numbers of adult stem cells (mesenchymal ...
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Hybrid embryos vote a good start, says BIA
Pharma Times (subscription) - London,UK
Last week’s parliamentary vote in favour of using interspecies or hybrid embryos for stem cell research is welcome but needs to be backed up with funding ...
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Saving your baby's stem cells at the dentist could save their life ...
KVUE - Austin,TX,USA
And already stem cell research is being done that could eventually treat conditions like diabetes, heart disease, leukemia, multiple sclerosis, parkinson’s, ...
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Novel role for SLPI in MOG-induced EAE revealed by spinal cord ...
7thSpace Interactive (press release) - New York,NY,USA
Adult neural stem cells were incubated with recombinant secretory leukocyte protease inhibitor (SLPI). Proliferation was assessed by BrdU incorporation, ...
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BioTech Buzz: How Much Is A CEO Worth?
Worcester Business Journal - Worcester,MA,USA
... and there were two encouraging late stage product clinical trials: one for stem-cell transplantation and the other for multiple sclerosis. ...
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