Wednesday, September 03, 2008

Wake Forest Doctors Working On Pill For Multiple Sclerosis

Wake Forest Doctors Working On Pill For Multiple Sclerosis
WFMY News 2 - Greensboro,NC,USA
Doctors say they're they're working on that answer with a pill called Laquinimod. It's in clinical trials right now, but doctors want to stress that it's ...

New Cases of Brain Infection Linked to Tysabri - Tampa,FL,USA
The multiple sclerosis drug Tysabri has been linked to two new cases of progressive multifocal leukoencephalopathy (PML) in Europe. ...

Opexa Therapeutics and Myelin Repair Foundation Partner on Novel ...
MarketWatch - USA
"Through our collaboration with Opexa and our analysis of patient samples from the Tovaxin Phase IIb study, we hope to discover novel therapeutic, ...

OPXA: Research Partnership w/Myelin Repair Foundation
Trading Markets (press release) - Los Angeles,CA,USA
... important insight to support the continued development of Tovaxin(R), Opexa's T-cell vaccine currently in Phase IIb clinical testing in MS patients. ...

Allos Therapeutics to Present at the 3rd Annual Citi Biotech Day
Centre Daily Times - Centre,PA,USA
WESTMINSTER, Colo. — Allos Therapeutics, Inc. (NASDAQ: ALTH), a biopharmaceutical company focused on developing and commercializing innovative small ...

Auction to benefit neurodegenerative disease research
News Transcript Tue, 02 Sep 2008 4:43 PM PDT
A live auction of fine art, sports memorabilia, music memorabilia and more, hosted by the Brandeis National Committee Harmony Chapter, will be held at Eagle Ridge Golf Club, 2 Augusta Blvd., Lakewood, Sept. 11. All funds raised will benefit the Science Laboratory Fund for research in neurodegenerative diseases such as Alzheimer's, Parkinson's, multiple sclerosis and others.


Dr. Girard

Neurologist, Hôtel-Dieu Hospital (CHUM)in Montreal, QC
View BIO


Q :

I’ve had secondary progressive MS for 16 years. Last year I was taking glatirmer acetate (Copaxone) every day. My neurologist thinks it is not a good idea to continue this treatment. I am now taking it twice a day because I wanted to continue. I’d like to know why this treatment provides neuronal protection for relapsing-remitting forms of MS, while it’s less effective for the progressive forms. Isn’t the protection of neurons the same?

A :

According to certain studies, it is indeed true that Copaxone seems to have a certain neuronal protective effect. In spite of that, Copaxone does not ensure complete protection against axonal degeneration. Several studies have shown that Copaxone is unfortunately not as effective on progressive forms of MS, whether primary or secondary. This lack of efficacy is also true for other immunomodulators such as interferons. Your neurologist is right to question the relevance of continuing to Copaxone in your case.
9/3/2008 9:30:45 PM
More answers from Dr. Marc Girard
More answers in the category: Treatment

 DISCLAIMER: Please be aware that this information does not necessarily represent the opinion of the MS Society of Canada, and is not intended as medical advice. For specific advice and opinion, always consult a physician.
© 2008 Multiple Sclerosis Society of Canada |


Daily Living with MS

Dr. Yeung

Director MS Clinical Trials Research Unit Foothills MS Clinic, Calgary
View BIO

Q :

Do you think the increase rate of women with MS while incidence rates in men have remained stable could be linked to the overall changes of women’s roles in society? Patterns of child birth, oral contraception and additional pressures on work stress have all changed dramatically in that period and there is some evidence suggesting pregnancy hormones can reverse or delay MS activity.

A :

The increasing rate of MS in women is a relatively recent observation. The underlying cause of this is unknown, but is being investigated by researchers such as Dr. D. Sadovnick in Vancouver.
9/3/2008 9:52:12 PM
More answers from Dr. Michael Yeung
More answers in the category: Daily Living with MS

Multiple Sclerosis 

In the Spotlight | More Topics | 
from Julie Stachowiak, Ph.D.

Some experts say that doctors can throw out all of the questionnaires and complicated diagnostic criteria that they use to determine if someone is depressed and just ask one or two questions: "Have you lost interest in things that you used to be interested in?" and "Have you felt depressed or sad much of the time?"

Apparently, a "yes" answer to one or both of these is a pretty good indicator of depression. However, what about the person suffering from fatigue related to multiple sclerosis (MS)? I can tell you that when I am fatigued (around 11:00 am on muggy July mornings, for instance), I sure as heck have no interest in anything except feeling better - and, damn straight, I am sad about it. Sometimes this feeling lasts for days on end. Last summer it was months in a row without relief.

Is this depression? Is this fatigue? Is it a combination? I guess what is hard here is not just seeking a diagnosis, but determining how to treat the problem - I think depression should be treated by psychiatrists, plain and simple. However, how many of them specialize in MS and would have a general understanding of what the physiological effects of MS-related fatigue are? If you are unfamiliar with the fatigue induced by MS, it sounds rather unbelievable (and, frankly, falls right along the lines of many of the depression symptoms).

Anyway, the point of all of this is that while there are treatments for both fatigue and depression, treating either or both of these in the patient with MS takes some skill and patience to get right. Remember, this is not your fault. Take care of yourselves.

In the Spotlight

MS-Related Fatigue
I probably don't have to tell anyone reading this that the fatigue that comes with MS is beyond what anyone could really believe possible without experiencing it. It is the most life-sapping, soul-crushing feeling there is. And, yes - just to reiterate - it is depressing.

Read the full articles:

MS-Related Depression
I know that much of depression is "organic," coming from chemical or other imbalances in the brain. However, I can also say that it is very lonely sometimes to have MS-related fatigue and feel desperate and misunderstood. Read the full article: Depression as a

Symptom of MS

Treating MS-Related Fatigue and Depression
On a more positive note, there are treatments available for both depression and fatigue. It might take awhile to find the right concoction or mix of therapies. You may find that exercise helps or that "talk therapy" is useful. Whatever the solution might eventually be, don't stop until you feel better. You can get relief.

Read the full articles:

More Topics 

Vitamin D

Getting Daily Dose of 'D'
RedOrbit - Dallas,TX,USA
Recent studies have shown that people with low levels of vitamin D may be at a higher risk of getting cancer, diabetes, multiple sclerosis, arthritis, ...

Vitamin D is helpful, but it's possible to overdose
South Coast Today - New Bedford,MA,USA
Last April, my doctor prescribed 50000 IU vitamin D once a week. I have been taking it ever since. I get lots of sun. I also take 600 mg of calcium with 200 ...

High doses of vitamin D safe for children
The News - International - Pakistan
NEW YORK: Giving school children very high doses of vitamin D is safe, and may be necessary to bring their blood levels of the nutrient up to the amount ...

Study backs low vitamin D-diabetes link - Istanbul,Istanbul,Turkey
The researchers found the men with the highest serum vitamin D levels were the least likely to have developed type 2 diabetes 22 years later. ...

Health check-up
Otago Daily Times - Dunedin,New Zealand
Vitamin D deficiency has been linked to a 26% greater risk of death in men and women, according to a US study confirming the importance of this essential ...

Federal Focus

More Info

Register to Vote

Election season is in full swing and the 2008 elections are just around the corner. With health care being a top domestic issue, you have the chance to join the voice of the MS community to make an important step towards change in the current system.

Now is the time to ensure that you are prepared to make your vote. First and foremost, you must be registered to vote in your state. Most state deadlines to register are coming up within the next several weeks. To find the registration deadlines and criteria that apply to your home state, please click here to visit the Declare Yourself website.

Take action now to guarantee your voice in the 2008 election by registering to vote today. It's quick and easy.

Election Season 2008

The chronic disease community as a whole will collectively have a stronger voice than ever with health care being one of the top domestic issues facing this election.

Click here to check out the Research America website, which provides a useful and extensive overview of each candidate and their positions on the top issues currently facing the United States. These candidates will continue to campaign until November, and you can have a successful impact on their positions with your voice and your vote. Make the most of your vote by researching your public officials and their position on top issues in the 2008 election.

Act now: this is your opportunity to make a difference.

Thank you for being a MS activist.

Join the movement at

To keep future MS activism messages out of your junk folder, add the following address to your contacts or safe sender list:

Sign Up to Be an MS Activist

Read the MS Activist Blog

Chapter Contacts for State Issues

Issue Briefs and Background

National MS Society Homepage


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