Thursday, November 01, 2007

Questions raised about drug being studied for MS Thu, 01 Nov 2007 6:30 AM PDT
A group of American scientists has warned other researchers that an acne drug being tested as a possible treatment for a variety of neurodegenerative diseases - including in Canada for multiple sclerosis - may actually cause harm.

Minocin Causes ALS to Worsen 25% Faster (Interview with Dr. Michael Swash, MD) - Insidermedicine

On the basis of these preliminary results, researchers from Columbia University and elsewhere, tested minocin as a treatment with ALS in more than 400 patients and compared their progress to patients on placebo.
Compared to the placebo-treated patients, those taking minocin deteriorated at a 25% faster rate according to the ALS functional rating scale. As a result, the researchers are reassessing the trials with minocin in other neurological diseases, such as Huntington’s disease, stroke, dementia, and multiple sclerosis.

Block on recruitment to continue
Irish Independent - Dublin,Ireland
... were now being denied care and treatment as HSE cutbacks reduced hours in care packages and delayed the administration of Tysabri, a new MS drug. ...
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Minocin Causes ALS to Worsen 25% Faster (Interview with Dr ...
Insider Medicine - Kingston,Ontario,Canada
Treatment with Rilutek (riluzole) should be considered for those with ALS. This medicine has been shown to reduce progression of the disease and may delay ...
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UPDATE 2-Bayer takes charges, higher Betaferon dose fails
Reuters - USA
Betaseron was Bayer's top selling drug last year with sales of 991 million euros, up 14 percent. Bayer Schering Pharma, a Bayer unit, said it expected sales ...
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BEYOND Study Fails to Show Superiority of Betaferon
FDA news (subscription) - Falls Church,VA,USA
German drugmaker Bayer-Schering Pharma's Phase III trial of Betaferon did not show statistically significant superiority of the 500-mcg Betaferon dose ...
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Bayer drops plans for 500 mcg Betaferon approval, writes off ... - USA
The study, which tested both doses of Betaferon against each other and also against Teva Pharmaceutical Industries Ltd's (NASDAQ:TEVA) Copaxone, ...
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Betaferon(R) 250 mcg de optimale dosis voor de behandeling van MS
Medical facts - Utrecht,Overijssel,Netherlands
Beyond studie laat geen superioriteit zien van Betaferon(R) 500 mcg ten opzichte van Betaferon 250(R) mcg en Copaxone(R). Bayer Schering Pharma kondigt ...
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Bayer's Betaferon Doesn't Work Better at Higher Dose (Update1)
Bloomberg - USA
Bayer gained Betaferon, also sold as Betaseron, in its 17 billion-euro purchase of German rival Schering AG. ``The standard Betaferon 250-mcg dose is the ...
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Bayer drops drug plan
Pittsburgh Tribune-Review - Pittsburgh,PA,USA
The company said that Bayer Schering Pharma AG, a unit set up after its acquisition of Schering AG in 2006, found in tests that a 500-microgram dose of ...
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