What causes chronic stress
Times of India - India
... investigator on National Space Biomedical Research Institute Radiation Effects Team and professor of molecular genetics, microbiology and immunology at ...
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Acorda Therapeutics Announces Receipt of ANDA Filing for Zanaflex ...
Die Welt - Germany
Acorda's lead clinical product, Fampridine-SR, is in a Phase 3 clinical trial to evaluate its safety and efficacy in improving walking ability in people ...
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What Is PDL Worth?
Motley Fool - USA
... the recent launch of Tysabri, and the potential for new royalty opportunities from the greater than 75 humanized monoclonal antibodies in development. ...
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"Step Inside MS" National Tour Brings First-of-Its-Kind Multiple ...
Business Wire (press release) - San Francisco,CA,USA
TYSABRI is a treatment approved for relapsing forms of MS in the United States and relapsing-remitting MS in the European Union. According to data that have ...
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In the Spotlight | More Topics |
from Julie Stachowiak, Ph.D.
Thank you everyone for your wonderful suggestions for books about MS to review - my virtual stack of books is about three feet high, so it will take some time, but look for your favorite to show up eventually (and keep the suggestions coming).
The first book that I reviewed was recommended by the most people. MS and Your Feelings: Handling the Ups and Downs of Multiple Sclerosis by Allison Shadday, LCSW, is one of the most thoughtful books that I have read on any subject. Check it out below.
On a personal note, I've been feeling a little "MSier" than usual, so there may be a little delay in responding to the wonderful e-mails that I have received from you all. Thank you again for writing, keep on sending your stories, tips and suggestions...and take care of yourselves.
MS and Your Feelings...You NEED This Book!
I'll admit it. I was skeptical about a book dealing with "feelings" having anything to do with how I was handling the difficulties of my MS. I mean, when I am looking for information, I want to know about pharmaceutical approaches and things that make me feel physically better right away.
I was blown away when I read this book. As I read through the chapters, I realized that there were some that applied to me now (Chapter 9: Sick and Tired of Feeling Sick and Tired) and some that did not apply to me now, but that I really could have used in the past (such as Chapter 1: Getting an Accurate Diagnosis). There are also several chapters that I know would help me, if I would take a deep breath and really dig deep down (for example, Chapter 8: Good Grief - Recognizing the Grieving Process). The author, Allison Shadday, LCSW, is not only an experienced counselor of people with MS, she has MS herself, which brings the suggestions and observations in this book to a new level - that of a friend who "gets it."
Needless to say, my initial skepticism turned into a realization of how much of this disease is about feelings, and how healthy we are is largely dependent on what is going on in our hearts and in our minds, not the number of lesions we have or the severity of our limps, tremors and numbness.
Bottom line: Get the book. Read it. Breathe easier and feel better. (Optional step: Thank me for recommending it.)
Read the entire review here Book Review of MS and Your Feelings: Handling the Ups and Downs of Multiple Sclerosis
- Depression and MS
- Medical Management of Depression in MS
- Talking About MS
- Stress and MS
- MS Symptoms and Signs
- What is MS?
- Causes of MS-Related Fatigue
St. John's Wort "Heads Up"
For those of you using St. John's wort to treat MS-related depression, just a gentle reminder: St. John's wort can potentially interfere with the effectiveness of oral contraceptives by lowering the concentration of them in the blood. In other words, your birth control pills will not work as well if you are taking St. John's wort, and you may get pregnant.
This is especially important information if you (or your female partner with MS) are currently using disease-modifying therapies and using birth control pills to prevent pregnancy.Read more...
The Growing "Army of Hormones" Against MS
In the body, estrogen binds to two types of receptor proteins: alpha (also known as estrodiol) and beta. Estrodiol has shown to have excellent results in both preventing damage to myelin, as well as disability. However, it comes with a risk of increasing chances for breast and uterine cancer in women.
This study targeted estrogen receptor beta. While the mice in this study still showed some inflammation and initial disability, there was no neurodegeneration. Eventually, the disability was greatly lessened.
The potential advantages to this treatment include: there was no neurodegeneration; it does not increase cancer risk (which is a potential danger of estrodiol and other estrogen-based approaches; it could be given to men, as does not cause feminine side effects, such as breast growth. Read more...
Volunteers with established spasticity resulting from Multiple
Sclerosis (MS)
needed for a research clinical trial.. This study is being conducted in:
- Mineola, NY
http://www.centerwatch.com/patient/studies/stu117622.html
Additional educational resource that may be of interest to you:
Volunteering for a Clinical Trial, a brief educational pamphlet. If you
would like to order this pamphlet click here:
http://www.centerwatch.com/bookstore/pubs_cons_brochureform.html
terwatch.com/patient/studies/stu117622.html
Additional educational resource that may be of interest to you:
Volunteering for a Clinical Trial, a brief educational pamphlet. If you
would like to order this pamphlet click here: http://www.centerwatch.com/bookstore/pubs_cons_brochureform.html">http://www.centerwatch.com/bookstore/pubs_cons_brochureform.html
Born lucky: Scientists discover 'skinny' gene
Scientists now say they have discovered the "skinny" gene. And they've found this lucky batch of DNA in a variety of animals, including humans, according to a report published Tuesday in the journal Cell Metabolism.
Research News
Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis
This small preliminary study looked at the possibility of using recombinant erythropoietin to treat progressive types of MS. This is a naturally occurring growth factor usually produced by the human kidney to stimulate production of blood cells, but may also have neuroprotective effects. It was shown to be safe and now large trials are needed.
authors: Ehrenreich H, Fischer B, Norra C, Schellenberger F, Stender N, Stiefel M, Sirén AL, Paulus W, Nave KA, Gold R, Bartels C
source: Brain. 2007 Aug 29; [Epub ahead of print]Germany.
This paper contributes to our knowledge about the complex genetic risk factors for developing MS.
authors: Gregory SG, Schmidt S, Seth P, Oksenberg JR, Hart J, Prokop A, Caillier SJ, Ban M, Goris A, Barcellos LF, Lincoln R, McCauley JL, Sawcer SJ, Compston DA, Dubois B, Hauser SL, Garcia-Blanco MA, Pericak-Vance MA, Haines JL; for the Multiple Sclerosis Genetics Group.
source: Nat Genet. 2007 Sep;39(9):1083-91. Epub 2007 Jul 29.
This paper reports more important work into the way genes contribute, in a complex way, to the risk of developing MS.
authors: International Multiple Sclerosis Genetics Consortium, Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ.
source: N Engl J Med. 2007 Aug 30;357(9):851-62. Epub 2007 Jul 29.
The authors report that patients treated with natalizumab, a newer therapy for severe MS, occasionally produce antibodies against the drug. It seems that these antibodies may sometimes alter its effectiveness.
authors: Calabresi PA, Giovannoni G, Confavreux C, Galetta SL, Havrdova E, Hutchinson M, Kappos L, Miller DH, O'connor PW, Phillips JT, Polman CH, Radue EW, Rudick RA, Stuart WH, Lublin FD, Wajgt A, Weinstock-Guttman B, Wynn DR, Lynn F, Panzara MA; for the AFFIRM and SENTINEL Investigators.
source: Neurology. 2007 Aug 29; [Epub ahead of print]
This randomised controlled trial showed that botox injected into the bladder wall was an effective treatment for resistant urinary symptoms in MS, improving patient’s reported quality of life scores.
authors: Schurch B, Denys P, Kozma CM, Reese PR, Slaton T, Barron RL.
source: Eur Urol. 2007 Sep;52(3):850-9. Epub 2007 Apr 19.
This technical paper describes how to measure loss of white matter in the brain, which can be a problem in MS, using MRI. The technique may help us to understand better what happens during the course of the condition over time.
authors: Pagani E, Horsfield MA, Rocca MA, Filippi M.
source: Magn Reson Med. 2007 Aug 30;58(3):527-534 [Epub ahead of print].
read moreMS News
Summaries of MS news from websites around the world.
Argentina marathon success
source: Esclerosis Múltiple Argentina
1,900 people took part in Esclerosis Múltiple Argentina's "Marathon Solidaria" to help raise funds and awareness for the society.
source: MS Society of Montenegro
An MS Society was established in Montenegro in July 2007 with the aim of supporting people affected by MS in the country and to raise awareness of the disease.
source: UK MS Society
Professor George Ebers from the University of Oxford gave a lecture on the effects of environmental factors (such as exposure to sunshine) and genetics on MS.
posted by Bill at 10:14 PM
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