Our 20 year old daughter was diagnosed at 18. She had many lesions
initially. She went right on Rebif with occasional iv steroids to
cool the exacerbations.

In December she had another MRI and was on iv steriods for 5 days.
Already by the second week in February she had to come home from
college because she was having symptoms again.

Tuesday she had an MRI and Wednesday she had a EEG. The EEG didn't
show anything. They only let her sleep for 4 hours Tuesday night so
they might see some seizures on the EEG. The MRI showed new lesions
so her doctor gave her the option to switch to Tysabri. She's going
to switch. She's relieved that she won't be burning holes in
herself with Rebif 3 times a week. She's never tolerated it well.
She has flu like symptoms for half a day to a full day after and the
injections sites look like a battle zone. One injection site
actually seemed to have all the fat cells burned off.

The doc said she shouldn't drive for a couple months so she
she went back to school today with her roommate's boyfriend
driving. She wants to go to the ballroom dance tomorrow night.
She has 2 weeks worth of rebif left and then I understand she has a
2 month dry-out period from Rebif before she can start Tysabri. In
two weeks she'll be home for spring break and can take it real
easy. That should take her two months out and she can start up
Tysabri after the end of the semester.

I read back and I see lots of folks have experience with Tysabri.
Please don't scare me. I'm trying to be optimistic that her
decision was the right one.